Both photocarcinogenesis and extrinsic skin aging have been attributed to the damaging effects of solar ultraviolet (UV) radiation. Soy isoflavones have also been reported to support skin health by additional mechanisms, which mayor may not be related to their antioxidant properties. Treatment of human fibroblasts with a soy isoflavone extract significantly reduces UV-induced matrix metalloproteinase-l secretion. Additionally, treatment with two different soy extracts, one containing approximately 20% isoflavones and one containing about 11% isoflavones plus 14% soy saponins, also enhances fibroblast collagen synthesis.
Overall, various components of soy, including isoflavones, saponins, and peptides, may have a variety of beneficial effects on skin health. The mechanisms of these effects appear to be varied and may include antioxidant potential, suppression of inflammatory processes, production of extracellular matrix (ECM) components, and suppression of enzymes involved in ECM breakdown.
Topical Application
Topical applications of soy and soy isoflavones have potential protective effects against photocarcinogenesis.
Dietary Consumption
Administration of the soy extract significantly improves parameters of skin roughness and nonsignificantly reduced transepidermal water loss, fine wrinkles, and UV radiation-induced thickening of the outer layer of skin.
Overall, various components of soy, including isoflavones, saponins, and peptides, may have a variety of beneficial effects on skin health. The mechanisms of these effects appear to be varied and may include antioxidant potential, suppression of inflammatory processes, production of extracellular matrix (ECM) components, and suppression of enzymes involved in ECM breakdown.
Topical Application
Topical applications of soy and soy isoflavones have potential protective effects against photocarcinogenesis.
Dietary Consumption
Administration of the soy extract significantly improves parameters of skin roughness and nonsignificantly reduced transepidermal water loss, fine wrinkles, and UV radiation-induced thickening of the outer layer of skin.
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